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KMID : 1189420110240010111
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2011 Volume.24 No. 1 p.111 ~ p.120
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Effect of Sophorae Radix-Skin Lotion on Acne
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Baek Sang-Chul
Jo Eun-Hee
Mendgerel
Park Min-Cheol
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Abstract
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Background and Objective :Sophorae Radix has been known as an useful plant with anti-inflammatory and anti-bacterial activity. Therefore, Sophorae Radix is expected to mitigate and prevent acne by inhibiting the activity of the sebaceous glands and acne bacterium. To evaluate anti-inflammation effect of Sophorae Radix, we applied Sophorae Radix-skin lotion on the patients with acne.
Methods: The Sophorae Radix-skin lotion was prepared by dissolving 1% ethanol extract of Sophorae Radix in skin lotion vehicle and treated 2 times everyday for 4 weeks on faces. Follow-up was performed with Janus facial analysis system.
Results:Sophorae Radix-skin lotion reduced sebum and porphyrin. However, the Sophorae Radix-skin lotion didn’t significantly reduced sebum and porphyrin compared with skin lotion vehicle control group.
Conslusion: These results showed that the Sophorae Radix-skin lotion could be used as a pharmaceutical material with anti-inflammatory effects by reducing sebum and porphyrin in acne patient with further clinical research.
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KEYWORD
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Sophorae Radix, porphyrin, acne, facial analysis system
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